VueScan is compatible with the Minolta Scan Elite 5400 II on Windows x86, Windows x64, Windows RT, Windows 10 ARM, Mac OS X and Linux. This scanner has an infrared lamp for scanning film. VueScan's 'Filter Infrared clean' option can be used to remove dust spots from film scans. This is similar to (and we think better than) the ICE and FARE algorithms. It scans with both visible light and infrared light in a single pass.

Infrared cleaning works well with all types of color negative and color slide film, including Kodachrome. However, silver-based black/white film doesn't work with infrared cleaning because the silver particles look the same in visible light and infrared light. If you're using Windows and you've installed a driver, VueScan's built-in drivers won't conflict with this. If you haven't installed a Windows driver for this scanner, VueScan will automatically install a driver.

You can use this scanner on Mac OS X and Linux without installing any other software. On Linux, you need to set up libusb device protections. Hearts and bones rescue.

How to run old Minolta scanners on Vista & 7: Page. Konica Minolta Dimage Scan Elite 5400 II. Kain Anderson suggest to use the 'legacy' driver under Windows 7.

If you have problems with this scanner hanging, try replacing the USB cable with a newer USB cable, preferably a shorter one. This scanner came with a low-quality USB cable, and is also sensitive to USB timing on faster computers.